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2024 · Knee Surgery & Related Research

Are the Final Postoperative Score and the Amount of Improvement the Same Question?

Adjusted R² values for 1-year WOMAC pain, stiffness and function scores were 0.017, 0.036 and 0.078. For change-score models, they were 0.881, 0.755 and 0.761, respectively.

Original Figure 5

There are three graphs showing the difference in improvement rates between pain and surgery before, and level-by-level.Enlarge Figure

Original Figure 5 compares improvement by quartile of preoperative WOMAC. The model includes postoperative joint motion, so it is not a validated predictor using preoperative information alone.

Sung Eun Kim, Du Hyun Ro, Myung Chul Lee, Hyuk-Soo Han. Can individual functional improvements be predicted in osteoarthritic patients after total knee arthroplasty?. Knee Surgery & Related Research (2024). https://doi.org/10.1186/s43019-024-00238-1

Evidence & Original SourceImage use terms

Participants and Methods

This single-center retrospective study developed multivariable linear regression models from demographic, imaging, surgical and examination data. All patients received cemented posterior-stabilized fixed-bearing TKA targeting neutral mechanical alignment. 976 TKA patients. WOMAC was assessed before surgery and at 1 year; more than 90% were women.

Main Findings

Adjusted R² values for 1-year WOMAC pain, stiffness and function scores were 0.017, 0.036 and 0.078. For change-score models, they were 0.881, 0.755 and 0.761, respectively. Mean WOMAC scores improved from 9.3 to 0.6 for pain, 3.9 to 0.9 for stiffness and 35.3 to 10.0 for physical function. Preoperative WOMAC, sex and postoperative joint motion were associated with several improvement measures.

The point of reading on surgery

Final postoperative status and the amount of improvement are different questions. Associations with joint motion and patellar treatment generate hypotheses, but a counseling tool requires external validation using only preoperative information.

Limitations

This single-center study had 1-year follow-up and no MCID analysis. Postoperative ROM was included in the model, so it is not a predictor with all inputs available before surgery. High change-score R² must be distinguished from low final-score R².

Let's put it briefly.

What did this study confirm?

Adjusted R² values for 1-year WOMAC pain, stiffness and function scores were 0.017, 0.036 and 0.078. For change-score models, they were 0.881, 0.755 and 0.761, respectively.

Can it be applied directly to individual patients' treatment decisions?

This single-center study had 1-year follow-up and no MCID analysis. Postoperative ROM was included in the model, so it is not a predictor with all inputs available before surgery. High change-score R² must be distinguished from low final-score R².

Keywords

Abstract · Original text

Sung Eun Kim, Du Hyun Ro, Myung Chul Lee, Hyuk-Soo Han. Can individual functional improvements be predicted in osteoarthritic patients after total knee arthroplasty? Knee surgery & related research. 2024;36(1):31. doi:10.1186/s43019-024-00238-1.

PURPOSE

Total knee arthroplasty (TKA) is an effective treatment for advanced osteoarthritis, and achieving optimal outcomes can be challenging due to various influencing factors. Previous research has focused on identifying factors that affect postoperative functional outcomes. However, there is a paucity of studies predicting individual postoperative improvement following TKA. Therefore, a quantitative prediction model for individual patient outcomes is necessary.

MATERIALS AND METHODS

Demographic data, radiologic variables, intraoperative variables, and physical examination findings were collected from 976 patients undergoing TKA. Preoperative and 1-year postoperative Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were assessed, and multivariate regression analysis was conducted to identify significant factors influencing one-year WOMAC scores and changes in WOMAC scores. A predictive model was developed on the basis of the findings.

RESULTS

The predictive accuracy of the model for 1-year WOMAC scores was poor (all adjusted R2 < 0.08), whereas the model for changes in WOMAC scores demonstrated strong predictability (all adjusted R2 > 0.75). Preoperative WOMAC scores, sex, and postoperative knee range of motion significantly affected all pain, stiffness, and physical function aspects of the WOMAC scores (all P < 0.05). Age, cerebrovascular disease, and patellar resurfacing were associated with changes in physical function (all P < 0.05).

CONCLUSIONS

The developed quantitative model demonstrated high accuracy in predicting changes in WOMAC scores after TKA. The identified factors influencing postoperative improvement in WOMAC scores can assist in optimizing patient outcomes after TKA.

© The Author(s) 2024

The original paper.

Can individual functional improvements be predicted in osteoarthritic patients after total knee arthroplasty?

Sung Eun Kim, Du Hyun Ro, Myung Chul Lee, Hyuk-Soo Han
Knee Surgery & Related Research · 2024

The first one examined.