R.Du Hyun RoOrthopedics & Research
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alignmentJLCAOA progressionHKAA
Knee Surgery, Sports Traumatology, Arthroscopy

2026 · Knee Surgery, Sports Traumatology, Arthroscopy

JLCA and coronal alignment progression: a longitudinal analysis of 10,841 knees

Rapid varus progression occurred in 34.0% (95% CI 32.8–35.1%), and rapid valgus progression in 25.7% (95% CI 21.2–30.7%).

Original Figure 2

Original standing long-leg radiographs illustrate alignment measurements, including the whole-leg axis and joint line.Enlarge Figure

Original standing long-leg radiographs illustrate alignment measurements, including the whole-leg axis and joint line.

Knee Surgery, Sports Traumatology, Arthroscopy (2026). DOI: 10.1002/ksa.70293 · Original Figure 2

Evidence & Original SourceImage use terms

Original Figure 3

The original graph separates progression direction and rate by baseline alignment. Annual progression of at least 0.50° in the same direction occurred in 34.0% of the varus group and 25.7% of the valgus group.Enlarge Figure

The original graph separates progression direction and rate by baseline alignment. Annual progression of at least 0.50° in the same direction occurred in 34.0% of the varus group and 25.7% of the valgus group.

Knee Surgery, Sports Traumatology, Arthroscopy (2026). DOI: 10.1002/ksa.70293 · Original Figure 3

Evidence & Original SourceImage use terms

Original Figure 9

ROC curves for rapid varus and valgus progression, with AUCs of 0.823 and 0.756, respectively.Enlarge Figure

ROC curves for rapid varus and valgus progression, with AUCs of 0.823 and 0.756, respectively.

Knee Surgery, Sports Traumatology, Arthroscopy (2026). DOI: 10.1002/ksa.70293 · Original Figure 9

Evidence & Original SourceImage use terms

The research question

What Characterizes Knees with Coronal Alignment Progression of at Least 0.50° per Year?

Participants and Methods

We assessed HKAA, JLCA and KL grades on standing long-leg radiographs. Baseline alignment was classified as varus (≤177°), neutral (177° < HKAA < 183°), or valgus (≥183°); multivariable logistic regression adjusted for age, sex and BMI. 10,841 limbs from a tertiary hospital; 6,519 were varus and 343 were valgus at baseline.

Main Findings

Rapid varus progression occurred in 34.0% (95% CI 32.8–35.1%), and rapid valgus progression in 25.7% (95% CI 21.2–30.7%). Model AUC was 0.823 in the varus group and 0.756 in the valgus group. JLCA, baseline alignment and KL grade were associated with rapid progression.

Implications for clinical and surgical practice

The study supports evaluating alignment progression alongside JLCA in OA follow-up. It does not directly prescribe target angles for HTO or TKA.

Limitations

This is a Level III observational study. It did not compare surgical alignment targets or correction amounts. An increase in odds should not be interpreted as an increase in absolute risk.

Let's put it briefly.

Which clinical question does this address?

The study supports evaluating alignment progression alongside JLCA in OA follow-up. It does not directly prescribe target angles for HTO or TKA.

Keywords

Abstract · Original text

Kee Soo Kang, Sang Yoon Kim, Byung Sun Choi, Hyuk-Soo Han, Chong Bum Chang, Du Hyun Ro. Large joint line convergence angle is associated with accelerated coronal alignment progression in osteoarthritic knees: A longitudinal analysis of 10,841 knees. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 2026. doi:10.1002/ksa.70293.

PURPOSE

Coronal knee alignment, determined by both joint line orientation and morphology of femur and tibia, alters with osteoarthritic progression, but its rate of change has not been systematically evaluated. This study aimed to categorise limbs according to the rate of hip-knee-ankle angle (HKAA) alteration and identify factors associated with accelerated alignment progression.

METHODS

10,841 limbs from a tertiary hospital were analysed. Alignment parameters and Kellgren-Lawrence (K-L) grades were measured on standing long-leg radiographs. Limbs were grouped by baseline HKAA as varus (HKAA ≤ 177°), neutral (177° < HKAA < 183°), or valgus (HKAA ≥ 183°). Accelerated and mild progression were defined as ≥ 0.50°/year and < 0.50°/year, respectively. Factors associated with accelerated coronal alignment progression were analysed using multivariable logistic regression.

RESULTS

Accelerated varus and valgus progression occurred in 34.0% (95% CI: 32.8%-35.1%) of the varus and 25.7% (21.2%-30.7%) of the valgus category, respectively. After adjustment for age, sex, and body mass index, greater baseline varus alignment, medial proximal tibial angle, and joint line convergence angle (JLCA) were associated with increased odds of accelerated varus progression by 4.9% (4.8%-5.0%), 10.8% (10.6%-10.9%), and 12.9% (12.7%-13.1%), respectively, in the varus category (n = 6519; AUC = 0.823). Higher K-L grade was associated with increased risk of accelerated varus progression compared with Grade 0 (I: 44.8% [44.5%-45.0%], II: 88.9% [88.6%-89.2%], III: 391.8% [346.1%-443.5%], and IV: 378.0% [305.0%-468.5%]; all p < 0.001). In the valgus category (n = 343), greater baseline HKAA and medially-opened JLCA increased the risk of accelerated valgus progression by 17.4% (3.6%-33.5%) and 19.4% (9.2%-28.8%), respectively (AUC = 0.756).

CONCLUSIONS

Approximately one-third of limbs with baseline HKAA ≤ 177° and about one-quarter of those with HKAA ≥ 183° exhibited ≥0.50° progression toward varus and valgus, respectively. Accelerated alignment change was associated with greater baseline HKAA, JLCA and higher baseline K-L grade, suggesting characteristics of this potential phenotype.

LEVEL OF EVIDENCE

Level III.

The original paper.

Large joint line convergence angle is associated with accelerated coronal alignment progression in osteoarthritic knees: A longitudinal analysis of 10,841 knees

Kee Soo Kang, Sang Yoon Kim, Byung Sun Choi, Hyuk-Soo Han, Chong Bum Chang, Du Hyun Ro
Knee Surgery, Sports Traumatology, Arthroscopy · 2026

Reviewed academic journal articles